ncRNA name | hsa-miR-21 |
ncRNA Category | miRNA |
Disease name | Graves ophthalmopathy |
Species | Homo sapiens |
Tissues/Cell_line | orbital tissues |
Methods | qPCR, Western blot, transfection, flow cytometry |
Expression pattern | up-regulated |
Functional description | The present study shows that miR-21 regulates cell proliferation, apoptosis, and differentiation in orbital fibroblasts from TAO, and acts as a mediator in TGF-β1-induced collagen production. |
PubMed ID | 25873777 |
Year | 2015 |
Title | MiRNA-21 promotes fibrosis in orbital fibroblasts from thyroid-associated ophthalmopathy. |
Drug-related ncRNA | NO |
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